HIDROXI-3-METIL-GLUTARIL-COENZIMA A REDUCTAZA
hydroxy-3-methyl-glutaryl-coenzyme A reductase / hydroxy-3-methyl-glutaryl-coenzyme A reductase. Enzima care par-ticipa in stadiul precoce al sintezei colesterolului, transformand HMG-CoA (sau p-hidroxi-p-metilglutaril co-enzima A) In acid mevalonic. Inhibitorii sai, denumiti *statine, sunt utilizati In te-rapie datorita efectului *hipocolesterolemiant. Abrev.: HMG-CoA reductaza.